RAD-140 (Testolone) Research Compound | where to buy rad 140

Notice: All products provided by Onyx Labs are strictly intended for laboratory research and analytical testing purposes only. They are not intended for human or animal consumption, diagnostic testing, clinical administration, or therapeutic use.

High-Purity RAD-140 Selective Androgen Receptor Modulator

RAD-140 (commonly known as Testolone) is an orally bioavailable, non-steroidal Selective Androgen Receptor Modulator (SARM). Engineered to exhibit high tissue-selectivity, RAD-140 binds with high affinity ( $K_i \approx 1 \text{ nM}$ ) to androgen receptors (AR) in bone and skeletal muscle tissue while displaying significantly lower affinity in prostate and seminal vesicle tissues.

In preclinical research, RAD-140 is extensively studied for its ability to stimulate muscle tissue hypertrophy, enhance protein retention, support bone density, and provide neuroprotective effects against androgen-deprivation stress without inducing the typical systemic androgenic side effects of traditional anabolic steroids.

Where to Buy RAD 140 with High-Purity Synthesis Standards?

When evaluating androgen receptor dynamics, muscle wasting models, or neuroprotective signaling pathways, acquiring verified chemical identity and exact batch purity is critical to scientific reproducibility.

Analytical Purity & Verification at Onyx Labs

Researchers considering where to buy rad 140 choose Onyx Labs for our unwavering commitment to laboratory transparency and quality control. Every batch of RAD-140 undergoes multi-stage testing, including High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS), to confirm a purity rating of ≥99%.

Precision Chemical Stability

Our RAD-140 compound is synthesized to exact structural parameters to guarantee high chemical stability and consistent solubility in standard organic laboratory solvents (such as DMSO or PEG-400), ensuring seamless integration into your research protocols.

Mechanisms of Action & Androgen Receptor Signaling

RAD-140 operates through tissue-selective transcription activation:

                    ┌──► Selective Binding to Skeletal Muscle AR (Upregulates Protein Synthesis)
                    │
RAD-140 (Testolone) ┼──► Selective Binding to Bone Tissue AR (Stimulates Osteoblast Activity)
                    │
                    └──► Minimal Prostate/Seminal Vesicle AR Binding (High Anabolic-to-Androgenic Ratio)

1. Tissue-Selective Androgen Receptor Agonism

RAD-140 acts as a full agonist in skeletal muscle tissue, triggering conformational changes in the androgen receptor that promote nuclear translocation and gene transcription responsible for muscle protein synthesis and nitrogen retention.

2. High Anabolic-to-Androgenic Ratio

In tissue selectivity studies, RAD-140 demonstrates a exceptionally high anabolic-to-androgenic ratio (~90:1 compared to testosterone’s 100:100 benchmark), making it a prime candidate for researching muscle wasting without androgenic side-effects.

3. Neuroprotective Signaling Pathways

Research indicates that RAD-140 exhibits neuroprotective properties in brain tissue models by modulating androgen-dependent neuronal survival pathways, offering an experimental framework for studying neurodegenerative conditions.

Technical Specifications & Storage Guidelines

Parameter	Specification
Product Name	RAD-140 (Testolone)
CAS Number	1182367-47-0
Chemical Formula	C20H16ClN5O2
Molecular Weight	393.83 g/mol
Purity Grade	≥99% (HPLC & Mass Spec Verified)
Physical Appearance	Off-White to Fine Crystalline Powder
Storage (Unreconstituted)	Store at 15°C – 25°C (59°F – 77°F) in a cool, dry place away from direct light.
Storage (In Solution)	Tightly sealed in ambient laboratory conditions; avoid heat and UV exposure.

FAQ: Sourcing & Where to Buy RAD 140 Research Reagents

How does RAD-140 differ from other SARMs like LGD-4033 or Ostarine?

While all SARMs selectively target androgen receptors, RAD-140 exhibits one of the highest receptor binding affinities ( $K_i \approx 1 \text{ nM}$ ) and a uniquely high anabolic-to-androgenic tissue selectivity ratio, making it ideal for potent muscle hypertrophic research.

How do I access the Certificate of Analysis (CoA) for my RAD-140 order?

When deciding where to buy rad 140 online, verifiable laboratory testing is crucial. Enter your lot tracking number in the MyOnyx portal or visit our dedicated Lab Results page to view complete Mass Spec and HPLC chromatograms for your specific batch.

Order RAD-140 from Onyx Research Labs

Equip your facility with synthesis-verified selective androgen receptor research compounds from Onyx Labs.

Quantity	1 bottle, 2 bottles, 3 bottles

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RAD-140